PTCB Certified Pharmacy Technician (PTCE)Order Entry and ProcessingEasy

A pharmacy technician is preparing to compound a 2% hydrocortisone cream. The prescription requires 60 grams of the cream. How many grams of pure hydrocortisone powder are needed?

  1. A1.2 grams
  2. B12.0 grams
  3. C3.0 grams
  4. D0.6 grams
Show answer & explanation

Correct answer: A. 1.2 grams

To calculate the amount of hydrocortisone powder needed, multiply the total quantity of the cream by the percentage strength. 2% of 60 grams is 1.2 grams.

Why the other options are wrong

  • B. Incorrect calculation; this would be 20% of 60 grams or 2% of 600 grams.
  • C. Incorrect calculation; this would be 5% of 60 grams.
  • D. Incorrect calculation; this would be 1% of 60 grams or 2% of 30 grams.

Percent Strength Calculation (w/w)

Calculates the amount of solute in a given amount of solution, expressed as a percentage of weight by weight.

  • Used for solid-in-solid or liquid-in-liquid preparations where both components are measured by weight.
  • Formula: (grams of solute / total grams of solution) * 100%.
  • Convert percentage to a decimal (e.g., 2% = 0.02) for calculations.

Memory trick: Percent means 'part of a hundred' by weight.

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