PTCB Certified Pharmacy Technician (PTCE)Order Entry and ProcessingMedium

A pharmacy technician is asked to prepare 500 mL of a 0.9% NaCl solution. How many grams of NaCl are needed?

  1. A0.9 grams
  2. B0.45 grams
  3. C9 grams
  4. D4.5 grams
Show answer & explanation

Correct answer: D. 4.5 grams

A 0.9% solution means 0.9 grams of solute per 100 mL of solution. To find the grams needed for 500 mL: (0.9 g / 100 mL) * 500 mL = 4.5 grams.

Why the other options are wrong

  • A. This is the amount in 100 mL, not 500 mL.
  • B. This would be for 50 mL of solution.
  • C. This would be for 1000 mL (1 liter) of solution.

Percent Strength Calculation (w/v)

Calculations involving percent strength (weight/volume) to determine the amount of solute needed to prepare a specific volume of solution.

  • Percent (w/v) means grams per 100 mL.
  • Use ratio-proportion or dimensional analysis.
  • Ensure units are consistent before calculation.

Memory trick: Concentration: Percent Means Per Hundred, Dose is Desired Amount.

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