PTCB Certified Pharmacy Technician (PTCE)Order Entry and ProcessingHard

A pharmacy receives an order for "Dopamine 400 mg in 250 mL D5W to infuse at 5 mcg/kg/min for a 70 kg patient." The pharmacy technician needs to calculate the infusion rate in mL/hr. What is the correct infusion rate?

  1. A21 mL/hr
  2. B31.5 mL/hr
  3. C13.13 mL/hr
  4. D10.5 mL/hr
Show answer & explanation

Correct answer: C. 13.13 mL/hr

First, calculate the total mg/hr: 5 mcg/kg/min * 70 kg * 60 min/hr = 21,000 mcg/hr = 21 mg/hr. Next, calculate mL/hr using the concentration: (250 mL / 400 mg) = 0.625 mL/mg. So, 0.625 mL/mg * 21 mg/hr = 13.125 mL/hr. Rounded appropriately, this is 13.13 mL/hr.

Why the other options are wrong

  • A. Incorrect, likely a miscalculation in concentration or conversion.
  • B. Incorrect, overestimation of the rate.
  • D. Incorrect calculation, possibly missing a conversion factor.

IV Drip Rate Calculation (mcg/kg/min)

A complex calculation involving patient weight, drug concentration, desired dose, and time to determine the appropriate infusion rate in mL/hr for IV medications.

  • Units must be consistent (e.g., mcg to mg, min to hr).
  • Formula: (Dose x Weight x Time) / Concentration.
  • Pay close attention to all conversion factors.

Memory trick: Drip Rate: Dose, Weight, Time, Concentration – Get It Right!

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