NHA Certified Phlebotomy Technician (CPT)Specimen HandlingEasy

A phlebotomy technician is preparing to aliquot a plasma specimen into multiple smaller tubes for different tests. Which of the following is the most important safety precaution to observe?

  1. APerforming the procedure under a fume hood.
  2. BUsing a new pipette for each aliquot.
  3. CWearing sterile gloves.
  4. DLabeling the new tubes before aliquoting.
Show answer & explanation

Correct answer: B. Using a new pipette for each aliquot.

Using a new pipette for each aliquot prevents cross-contamination between the original specimen and the new tubes or between different aliquots, ensuring accurate results and maintaining specimen integrity.

Why the other options are wrong

  • A. A fume hood is typically used for handling hazardous chemicals or volatile substances, not routinely for aliquoting blood specimens unless specific volatile analytes are involved.
  • C. Wearing sterile gloves is important for aseptic technique but not the most critical safety precaution specific to preventing cross-contamination during aliquoting.
  • D. Labeling new tubes before aliquoting is essential for identification but is a pre-analytic step for organization, not a safety precaution against contamination during the aliquoting process itself.

Aliquot Safety

Aliquoting involves transferring a portion of a specimen into separate tubes. Preventing cross-contamination is paramount to maintain specimen integrity and ensure accurate test results.

  • Use a new pipette for each aliquot.
  • Avoid splashing.
  • Wear PPE (gloves, lab coat, eye protection).

Memory trick: New tip for every sip, keeps the samples pure, no slip!

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