NHA Certified Phlebotomy Technician (CPT)Specimen HandlingHard

A phlebotomy technician is preparing to send a specimen for a prothrombin time (PT) and activated partial thromboplastin time (aPTT) to an off-site laboratory. Which of the following is the correct transport condition?

  1. ACentrifuge and transport plasma on ice.
  2. BTransport whole blood at room temperature.
  3. CCentrifuge and transport plasma at room temperature.
  4. DTransport whole blood at 37°C.
Show answer & explanation

Correct answer: C. Centrifuge and transport plasma at room temperature.

Coagulation specimens for PT/aPTT require prompt separation of plasma from cells. Once separated, the plasma can be transported at room temperature for up to 24 hours for PT and 4 hours for aPTT, or frozen for longer stability. Whole blood should not be transported for extended periods due to cellular metabolism affecting coagulation factors.

Why the other options are wrong

  • A. While some specialized coagulation tests require freezing, routine PT/aPTT plasma can be transported at room temperature. Icing plasma is generally not standard for these tests.
  • B. Transporting whole blood for PT/aPTT allows cellular metabolism to occur, which consumes coagulation factors and can lead to inaccurate results if delayed.
  • D. Transporting whole blood at 37°C would accelerate cellular metabolism and degradation of coagulation factors, leading to highly inaccurate results.

Coagulation Specimen Transport

Coagulation specimens (PT/aPTT) require prompt centrifugation to separate plasma from cells. The plasma can then be transported at room temperature for specific timeframes or frozen for longer storage.

  • Separate plasma from cells quickly.
  • Plasma can be transported at room temperature (e.g., within 24h for PT).
  • Freezing is for longer storage or specific tests.

Memory trick: Coagulation Plasma: Centrifuge, then Carry Calmly.

More Specimen Handling questions