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A genetic counselor is explaining the inheritance pattern of a rare genetic disorder to a couple. The disorder appears in every generation, affects males and females equally, and an affected parent has a 50% chance of passing the disorder to each child, regardless of the child's sex. This pattern is consistent with which type of inheritance?

  1. AMitochondrial
  2. BX-linked recessive
  3. CAutosomal recessive
  4. DAutosomal dominant
Show answer & explanation

Correct answer: D. Autosomal dominant

Autosomal dominant inheritance is characterized by the trait appearing in every generation, affecting males and females equally, and an affected individual having a 50% chance of passing the allele to each offspring. This matches the described scenario.

Why the other options are wrong

  • A. Mitochondrial inheritance is passed only from mother to all children, which does not fit the 'affected males and females equally' and 'affected parent' criteria.
  • B. X-linked recessive disorders typically affect males more frequently and often skip generations.
  • C. Autosomal recessive disorders often skip generations and require two copies of the affected allele for expression.

Autosomal Dominant Inheritance

A pattern of inheritance where a single copy of an altered gene on a non-sex chromosome (autosome) is sufficient to cause the trait or disease.

  • Trait appears in every generation.
  • Affected individuals have at least one affected parent.
  • Males and females are affected equally.
  • Affected parent has 50% chance of transmitting to each child.

Memory trick: Dominant Always Shows, Recessive Really Hides.

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