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A patient experiences a sudden, severe allergic reaction after consuming a food item. Symptoms include widespread hives, swelling of the face and throat, difficulty breathing, and a rapid drop in blood pressure. Which type of immune response is most likely occurring?

  1. AType III Hypersensitivity (Immune Complex)
  2. BType I Hypersensitivity (Anaphylactic)
  3. CType II Hypersensitivity (Cytotoxic)
  4. DType IV Hypersensitivity (Delayed-Type)
Show answer & explanation

Correct answer: B. Type I Hypersensitivity (Anaphylactic)

The symptoms described, including widespread hives, swelling, difficulty breathing, and a rapid drop in blood pressure, are characteristic of anaphylaxis, which is a severe, systemic Type I hypersensitivity reaction. This type of reaction is immediate and can be life-threatening.

Why the other options are wrong

  • A. Type III hypersensitivity involves immune complex deposition, leading to inflammation in tissues, not typically immediate widespread anaphylactic shock.
  • C. Type II hypersensitivity involves antibody-mediated destruction of cells, not widespread systemic reactions to allergens.
  • D. Type IV hypersensitivity is a delayed cell-mediated response, occurring hours to days after exposure, unlike the immediate reaction described.

Type I Hypersensitivity

An immediate allergic reaction mediated by IgE antibodies, often leading to symptoms like hives, swelling, and in severe cases, anaphylaxis.

  • Mediated by IgE antibodies
  • Rapid onset (minutes)
  • Can be localized or systemic (anaphylaxis)

Memory trick: ACID: Anaphylactic, Cytotoxic, Immune-complex, Delayed

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