PTCB Certified Pharmacy Technician (PTCE)MedicationsMedium

A pharmacy technician is preparing a non-sterile compound. The formula requires 0.5 mL of a liquid ingredient. Which of the following measuring devices would provide the MOST accurate measurement for this volume?

  1. AA 100 mL graduated cylinder
  2. BA 50 mL conical graduate
  3. CA 1 mL tuberculin syringe
  4. DA 10 mL oral syringe
Show answer & explanation

Correct answer: C. A 1 mL tuberculin syringe

For measuring small liquid volumes (less than 1 mL), a tuberculin syringe provides the highest accuracy. Graduated cylinders and conical graduates are less accurate for very small volumes, and a 10 mL oral syringe, while better than larger graduates, is still less precise than a 1 mL tuberculin syringe for 0.5 mL.

Why the other options are wrong

  • A. A 100 mL graduated cylinder is far too large for accurate measurement of 0.5 mL.
  • B. A 50 mL conical graduate is not precise enough for such a small volume.
  • D. A 10 mL oral syringe is better than larger graduates but less accurate for 0.5 mL than a 1 mL syringe.

Measuring Small Liquid Volumes

The principle of selecting the smallest appropriate measuring device that can accurately measure a given liquid volume, typically using syringes for volumes less than 1 mL.

  • Use smallest device for accuracy.
  • Syringes are most accurate for small volumes.
  • Graduated cylinders/conical graduates for larger volumes.

Memory trick: Small Volume, Small Syringe, Super Accurate.

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