PTCB Certified Pharmacy Technician (PTCE)MedicationsMedium

A pharmacy technician is preparing a non-sterile compound that requires the use of a Class A prescription balance. According to USP <1176> 'Prescription Balances and Volumetric Apparatus,' what is the minimum weighable quantity for a Class A balance with a sensitivity requirement of 6 mg and a maximum acceptable error of 5%?

  1. A120 mg
  2. B12 mg
  3. C6 mg
  4. D600 mg
Show answer & explanation

Correct answer: A. 120 mg

The minimum weighable quantity (MWQ) is calculated using the formula: MWQ = Sensitivity Requirement / Maximum Acceptable Error. So, MWQ = 6 mg / 0.05 = 120 mg.

Why the other options are wrong

  • B. This would be the MWQ if the error was 50%, which is incorrect.
  • C. This is the sensitivity requirement, not the MWQ.
  • D. This is incorrect and would imply a much smaller acceptable error.

Minimum Weighable Quantity (MWQ)

The smallest amount of a substance that can be accurately weighed on a given balance, considering its sensitivity and an acceptable error percentage.

  • Ensures accuracy in compounding
  • Calculated using sensitivity and acceptable error
  • Essential for potent substances

Memory trick: Mighty Weighing Quantities Ensure Accuracy.

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