PTCB Certified Pharmacy Technician (PTCE)MedicationsEasy

A pharmacy technician is preparing a non-sterile compound requiring 30 grams of an ingredient. The balance used has a sensitivity requirement of 6 mg and a minimum weighable quantity (MWQ) of 120 mg. To ensure accuracy, which of the following is the most appropriate action?

  1. ARequest a different balance with a higher sensitivity.
  2. BWeigh the 30 grams directly on the balance.
  3. CUse an aliquot method to weigh the ingredient.
  4. DRound the quantity to the nearest gram for easier measurement.
Show answer & explanation

Correct answer: B. Weigh the 30 grams directly on the balance.

The minimum weighable quantity (MWQ) is the smallest amount that can be weighed with acceptable accuracy on a given balance. Since 30 grams (30,000 mg) is significantly greater than the MWQ of 120 mg, the ingredient can be accurately weighed directly.

Why the other options are wrong

  • A. A different balance is not necessary as the current balance is suitable for this quantity.
  • C. The aliquot method is used when the desired quantity is less than the MWQ, which is not the case here.
  • D. Rounding the quantity would introduce an inaccuracy and is not an appropriate method for compounding.

Minimum Weighable Quantity (MWQ)

The smallest amount of a substance that can be weighed with acceptable accuracy (typically within 5% error) on a specific balance.

  • Calculated as (Sensitivity Requirement / Acceptable Error) * 100%
  • Ensures accurate measurement for compounding.
  • If quantity is below MWQ, aliquot method must be used.

Memory trick: Measure carefully, MWQ ensures no tiny slips.

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