NHA Certified Clinical Medical Assistant (CCMA)Foundational Knowledge and Basic ScienceMedium

A patient reports experiencing frequent heartburn and a sour taste in their mouth, especially after meals. The medical assistant suspects gastroesophageal reflux disease (GERD). Which of the following anatomical structures is most likely malfunctioning in this condition?

  1. AIleocecal valve
  2. BPyloric sphincter
  3. CLower esophageal sphincter
  4. DUpper esophageal sphincter
Show answer & explanation

Correct answer: C. Lower esophageal sphincter

GERD is characterized by the reflux of stomach acid into the esophagus, which occurs due to a weakening or relaxation of the lower esophageal sphincter, allowing acid to flow backward.

Why the other options are wrong

  • A. The ileocecal valve separates the small and large intestines and is unrelated to esophageal reflux.
  • B. The pyloric sphincter regulates the passage of food from the stomach to the small intestine, not related to reflux into the esophagus.
  • D. The upper esophageal sphincter controls the passage of food from the pharynx into the esophagus and prevents air from entering the esophagus, not stomach acid reflux.

Lower Esophageal Sphincter (LES)

A ring of muscle at the junction of the esophagus and stomach that normally prevents stomach acid from refluxing into the esophagus.

  • Acts as a barrier to gastric acid.
  • Its relaxation or weakness is a primary cause of GERD.
  • Located just above the diaphragm.

Memory trick: LES's laxity lets acid leap upwards.

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