NHA Certified Clinical Medical Assistant (CCMA)Foundational Knowledge and Basic ScienceHard

A patient is prescribed a medication that inhibits the reuptake of serotonin, aiming to increase its availability in the synaptic cleft. This medication is most likely classified as which of the following?

  1. ABeta-blocker
  2. BAntihistamine
  3. CSSRI (Selective Serotonin Reuptake Inhibitor)
  4. DNSAID (Nonsteroidal Anti-Inflammatory Drug)
Show answer & explanation

Correct answer: C. SSRI (Selective Serotonin Reuptake Inhibitor)

The description 'inhibits the reuptake of serotonin' directly defines the mechanism of action for Selective Serotonin Reuptake Inhibitors (SSRIs), a class of antidepressants that increase serotonin levels in the brain to improve mood.

Why the other options are wrong

  • A. Beta-blockers block beta-adrenergic receptors, used for cardiovascular conditions like hypertension.
  • B. Antihistamines block histamine receptors, primarily used for allergies.
  • D. NSAIDs inhibit prostaglandin synthesis, used for pain and inflammation.

Selective Serotonin Reuptake Inhibitors (SSRIs)

A class of antidepressant medications that work by increasing the amount of serotonin in the brain's synaptic cleft by blocking its reabsorption into the presynaptic neuron.

  • Primary treatment for depression, anxiety disorders, and some other conditions.
  • Mechanism: blocks serotonin transporters (SERT).
  • Examples: Fluoxetine, Sertraline, Escitalopram.

Memory trick: Drugs Divide into Categories, Each for a Cause.

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