PTCB Certified Pharmacy Technician (PTCE)Federal RequirementsHard

A patient calls the pharmacy requesting a refill for their prescription of Lyrica (pregabalin), a Schedule V controlled substance. The patient states they have already received 6 refills within the past 5 months and their prescription was originally written 7 months ago. Based on federal regulations, what should the technician advise the patient?

  1. AThe patient can receive one more refill, as long as it's within 6 months of the original fill date.
  2. BThe prescription has expired, and no more refills are allowed.
  3. CThe prescription is valid for 1 year and can have unlimited refills, so it can be refilled.
  4. DThe patient needs a new prescription because they have exceeded the 5-refill limit.
Show answer & explanation

Correct answer: B. The prescription has expired, and no more refills are allowed.

Schedule V controlled substance prescriptions are valid for 6 months from the date of issue and can have a maximum of 5 refills within that 6-month period. Since the prescription was written 7 months ago, it has expired, regardless of the number of refills already dispensed.

Why the other options are wrong

  • A. Incorrect. The 6-month validity period has already passed, so no more refills are allowed.
  • C. Incorrect; Schedule V prescriptions are not valid for 1 year and do not have unlimited refills.
  • D. While the 5-refill limit is a factor, the primary reason for denial here is the expiration of the prescription due to time (7 months vs. 6-month validity).

CIII-V Expiration Rules

Federal law dictates that prescriptions for Schedule III, IV, and V controlled substances expire 6 months after the date of issue, regardless of the number of refills remaining.

  • 6-month validity for CIII-V.
  • Maximum 5 refills within that 6-month period.
  • Whichever comes first (6 months or 5 refills) causes expiration.
  • New prescription required after expiration.

Memory trick: Six months Or Five refills, whichever comes first, the prescription dies.

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