PTCB Certified Pharmacy Technician (PTCE)Federal RequirementsEasy

A patient approaches the pharmacy counter asking for an antihistamine to treat their seasonal allergies. They explicitly state they do not have a prescription. Which of the following is an example of an over-the-counter (OTC) antihistamine that can be directly purchased without a prescription?

  1. ALoratadine
  2. BFexofenadine with pseudoephedrine (Rx strength)
  3. CPromethazine
  4. DHydroxyzine
Show answer & explanation

Correct answer: A. Loratadine

Loratadine (e.g., Claritin) is a common second-generation antihistamine available over-the-counter for allergy relief.

Why the other options are wrong

  • B. While fexofenadine is OTC, the 'with pseudoephedrine (Rx strength)' implies a combination product that might be prescription-only or BTC, and pseudoephedrine itself has sales restrictions.
  • C. Promethazine is a prescription-only antihistamine often used for nausea and sedation.
  • D. Hydroxyzine is a prescription-only antihistamine with sedative properties.

Over-the-Counter (OTC) Medications

Medications that can be purchased without a prescription, generally considered safe and effective for use by the general public when directions are followed.

  • Do not require a doctor's order.
  • Available directly from pharmacy shelves or other retail stores.
  • Examples include many pain relievers, cold remedies, and allergy medications.

Memory trick: Drugs are either RX, OTC, or BTC, each with rules.

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