Certified Medical Assistant (CMA AAMA)PharmacologyMedium

A patient reports taking fluoxetine (Prozac) for depression. The medical assistant should be aware that this medication belongs to which drug class?

  1. ABenzodiazepine
  2. BMonoamine Oxidase Inhibitor (MAOI)
  3. CSelective Serotonin Reuptake Inhibitor (SSRI)
  4. DTricyclic Antidepressant (TCA)
Show answer & explanation

Correct answer: C. Selective Serotonin Reuptake Inhibitor (SSRI)

Fluoxetine (Prozac) is a well-known antidepressant that belongs to the class of Selective Serotonin Reuptake Inhibitors (SSRIs). SSRIs work by increasing the level of serotonin in the brain.

Why the other options are wrong

  • A. Benzodiazepines (e.g., diazepam) are typically used for anxiety and have sedative properties, not primarily for depression.
  • B. MAOIs (e.g., phenelzine) are powerful antidepressants with significant dietary restrictions and drug interactions.
  • D. TCAs (e.g., amitriptyline) are an older class of antidepressants with more side effects.

Selective Serotonin Reuptake Inhibitors (SSRIs)

SSRIs are a class of antidepressants that primarily block the reabsorption (reuptake) of serotonin in the brain, thereby increasing the availability of serotonin to improve mood.

  • First-line treatment for depression, anxiety disorders.
  • Examples: fluoxetine, sertraline, paroxetine, escitalopram.
  • Generally fewer side effects than TCAs or MAOIs.

Memory trick: SSRIs Make Serotonin Soar!

More Pharmacology questions