Certified Medical Assistant (CMA AAMA)PharmacologyEasy

A physician writes a prescription for oxycodone, a Schedule II controlled substance. Which of the following best describes the prescribing requirements for this classification?

  1. APrescription must be written or electronically transmitted, and no refills are permitted
  2. BPrescription may be refilled up to five times within six months
  3. CPrescription may be called in by phone with unlimited refills
  4. DMedication is available without a prescription but must be logged in a pharmacy record book
Show answer & explanation

Correct answer: A. Prescription must be written or electronically transmitted, and no refills are permitted

Schedule II drugs have a high potential for abuse and require a written or electronically transmitted prescription with no refills allowed; a new prescription is needed each time. Verbal orders are only permitted in emergencies and must be followed by a written prescription.

Why the other options are wrong

  • B. Refills up to five times in six months describe Schedule III–V, not Schedule II.
  • C. Schedule II drugs cannot be called in with unlimited refills due to high abuse potential.
  • D. Schedule II drugs are never available without a prescription.

Schedule II Controlled Substances

Drugs with high abuse potential but accepted medical use, requiring written/e-prescription with no refills.

  • Examples: oxycodone, morphine, fentanyl, methylphenidate
  • No telephone refills except emergency supply
  • New prescription required for each fill

Memory trick: 'Two means TOO risky to refill'

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