NCLEX-RNPhysiological AdaptationMedium

A client with a history of frequent vomiting due to hyperemesis gravidarum has the following labs: pH 7.50, HCO3- 32 mEq/L, PaCO2 44 mmHg, potassium 3.0 mEq/L. Which acid-base disorder does the nurse identify?

  1. AMetabolic acidosis
  2. BMetabolic alkalosis
  3. CRespiratory alkalosis
  4. DRespiratory acidosis
Show answer & explanation

Correct answer: B. Metabolic alkalosis

Loss of gastric hydrochloric acid from prolonged vomiting causes metabolic alkalosis, evidenced by an elevated pH (>7.45) and elevated HCO3- (>26 mEq/L); the near-normal PaCO2 shows minimal respiratory compensation, and hypokalemia commonly accompanies this due to vomiting and the kidney's compensatory potassium wasting.

Why the other options are wrong

  • A. Metabolic acidosis would present with a low pH and low HCO3-, opposite of these findings.
  • C. Respiratory alkalosis would show a low PaCO2, not elevated HCO3- as the primary abnormality.
  • D. Respiratory acidosis would show a low pH with elevated PaCO2.

Metabolic Alkalosis from Vomiting

Loss of gastric acid (HCl) through vomiting or NG suction raises serum bicarbonate and pH, causing metabolic alkalosis.

  • Common causes: vomiting, NG suction, diuretics, antacid overuse
  • Often accompanied by hypokalemia and hypochloremia
  • pH >7.45, HCO3- >26 mEq/L
  • Treatment addresses underlying cause and replaces electrolytes

Memory trick: Vomiting Voids acid, raising pH and bicarb

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