NCLEX-RNPhysiological AdaptationHard

A nurse is caring for a client receiving mechanical ventilation for acute respiratory distress syndrome (ARDS). Which ventilator strategy is most consistent with current lung-protective guidelines?

  1. AHigh tidal volumes with high FiO2
  2. BHigh tidal volumes with low PEEP
  3. CLow tidal volumes with adequate PEEP
  4. DPermissive hyperventilation to normalize PaCO2
Show answer & explanation

Correct answer: C. Low tidal volumes with adequate PEEP

Lung-protective ventilation for ARDS uses low tidal volumes (approximately 6 mL/kg of predicted body weight) with adequate PEEP to prevent alveolar collapse and minimize ventilator-induced lung injury, while permitting mild hypercapnia (permissive hypercapnia, not hyperventilation).

Why the other options are wrong

  • A. High tidal volumes are contraindicated; high FiO2 also risks oxygen toxicity.
  • B. High tidal volumes worsen alveolar overdistension and lung injury in ARDS.
  • D. Permissive hypercapnia (allowing elevated CO2), not hyperventilation, is the accepted strategy.

ARDS Lung-Protective Ventilation

Ventilator strategy using low tidal volumes and adequate PEEP to minimize further lung injury in ARDS.

  • Tidal volume target ~6 mL/kg predicted body weight
  • PEEP keeps alveoli open, improves oxygenation
  • Permissive hypercapnia is acceptable trade-off
  • Goal is to reduce ventilator-induced lung injury

Memory trick: Low and Slow protects the alveoli

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