NCLEX-RNPhysiological AdaptationHard

A client sustains a fracture of the femur in a motor vehicle collision. Approximately 36 hours later, the client develops sudden dyspnea, confusion, and a petechial rash across the chest and neck. Oxygen saturation is 88% on room air. Which condition does the nurse suspect?

  1. APulmonary embolism from a venous thrombus
  2. BAcute exacerbation of asthma
  3. CCompartment syndrome of the affected limb
  4. DFat embolism syndrome
Show answer & explanation

Correct answer: D. Fat embolism syndrome

Fat embolism syndrome classically occurs 24–72 hours after a long bone fracture and presents with the triad of respiratory distress, neurologic changes (confusion), and a petechial rash on the chest, neck, and axillae, caused by fat globules entering the bloodstream and lodging in the pulmonary and cerebral capillaries.

Why the other options are wrong

  • A. PE typically presents with pleuritic chest pain and does not classically cause a petechial rash.
  • B. Asthma exacerbation would not explain the rash, confusion, or recent fracture history.
  • C. Compartment syndrome causes localized limb pain and pallor, not systemic respiratory and neurologic findings.

Fat Embolism Syndrome

A complication of long bone or pelvic fractures where fat globules enter the circulation and lodge in pulmonary and cerebral capillaries, causing respiratory distress, altered mental status, and petechiae.

  • Onset typically 24–72 hours after fracture
  • Classic triad: hypoxemia, neurologic changes, petechial rash on chest/neck/axillae
  • Management is supportive: oxygen, fracture stabilization, and monitoring for ARDS

Memory trick: Break a big bone, fat roams, rash and confusion come home

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