NCLEX-PN® ExaminationPhysiological AdaptationEasy

A client with a history of heart failure is prescribed furosemide 40 mg PO daily. The nurse should instruct the client to monitor for which of the following electrolyte imbalances as a potential adverse effect?

  1. AHypernatremia
  2. BHyperkalemia
  3. CHypercalcemia
  4. DHypokalemia
Show answer & explanation

Correct answer: D. Hypokalemia

Furosemide is a loop diuretic that works by inhibiting sodium and chloride reabsorption in the loop of Henle, leading to increased excretion of water, sodium, chloride, and importantly, potassium. Therefore, hypokalemia is a common and significant adverse effect.

Why the other options are wrong

  • A. Furosemide promotes sodium excretion, so hypernatremia is unlikely; hyponatremia is a more common fluid/electrolyte imbalance.
  • B. Furosemide causes potassium excretion, leading to hypokalemia, not hyperkalemia.
  • C. Loop diuretics can sometimes increase calcium excretion, potentially leading to hypocalcemia, not hypercalcemia.

Furosemide Electrolyte Imbalance

Furosemide, a loop diuretic, primarily causes the excretion of potassium, leading to hypokalemia. Clients on furosemide require regular monitoring of potassium levels.

  • Loop diuretics inhibit reabsorption in the loop of Henle.
  • Increases excretion of Na, Cl, K, and water.
  • Hypokalemia is a common and serious side effect.

Memory trick: Furosemide's Flow: K+ Goes Low

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