NCLEX-PN® ExaminationPhysiological AdaptationHard

The nurse is caring for a client with a new diagnosis of diabetes insipidus (DI). Which of the following findings would the nurse anticipate?

  1. ASpecific gravity of urine 1.002, serum osmolality 305 mOsm/kg, increased thirst.
  2. BSpecific gravity of urine 1.010, serum osmolality 275 mOsm/kg, decreased urine output.
  3. CSpecific gravity of urine 1.020, serum osmolality 295 mOsm/kg, normal urine output.
  4. DSpecific gravity of urine 1.030, serum osmolality 280 mOsm/kg, decreased thirst.
Show answer & explanation

Correct answer: A. Specific gravity of urine 1.002, serum osmolality 305 mOsm/kg, increased thirst.

Diabetes insipidus (DI) is characterized by a deficiency of antidiuretic hormone (ADH) or the kidneys' inability to respond to ADH. This leads to the excretion of large amounts of dilute urine, resulting in a very low urine specific gravity (<1.005). The excessive water loss causes dehydration, leading to increased serum osmolality (>295 mOsm/kg) and intense thirst (polydipsia) as the body tries to compensate.

Why the other options are wrong

  • B. Normal urine specific gravity and low serum osmolality with decreased urine output are inconsistent with DI.
  • C. Normal urine specific gravity, serum osmolality, and urine output are inconsistent with DI.
  • D. High urine specific gravity and normal serum osmolality with decreased thirst are inconsistent with DI.

Diabetes Insipidus (DI) Diagnostics

A disorder caused by ADH deficiency or renal insensitivity to ADH, leading to excessive excretion of dilute urine and profound thirst.

  • Cardinal symptoms: polyuria (up to 20 L/day) and polydipsia.
  • Urine specific gravity is very low (<1.005).
  • Serum osmolality is high (>295 mOsm/kg) due to dehydration.
  • Serum sodium is often high (hypernatremia).

Memory trick: DI = Dry Inside, Dilute Out!

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