NCLEX-PN® ExaminationPhysiological AdaptationEasy

A client is experiencing an exacerbation of asthma. The nurse notes expiratory wheezing, productive cough, and uses of accessory muscles. The peak expiratory flow rate (PEFR) is 60% of the client's personal best. Which medication should the nurse anticipate administering FIRST?

  1. AInhaled fluticasone
  2. BNebulized albuterol
  3. CIntravenous magnesium sulfate
  4. DOral prednisone
Show answer & explanation

Correct answer: B. Nebulized albuterol

The client's symptoms (wheezing, cough, accessory muscle use) and PEFR of 60% of personal best indicate an acute asthma exacerbation. Short-acting beta-agonists (SABAs) like albuterol are the first-line treatment for acute bronchospasm, as they rapidly relax bronchial smooth muscle, improving airflow. Nebulized administration provides quick and effective delivery.

Why the other options are wrong

  • A. Fluticasone (inhaled corticosteroid) is a long-term controller medication, not for acute exacerbations.
  • C. Magnesium sulfate may be used in severe, refractory asthma, but it is not the first-line treatment for an acute exacerbation.
  • D. Prednisone (systemic corticosteroid) is used for inflammation but has a delayed onset and is not for immediate bronchodilation.

Acute Asthma Exacerbation Treatment

A worsening of asthma symptoms (wheezing, cough, dyspnea, chest tightness) requiring immediate intervention to relieve bronchospasm and inflammation.

  • First-line treatment: Short-acting beta-agonists (SABAs) like albuterol.
  • SABAs provide rapid bronchodilation.
  • Systemic corticosteroids (e.g., prednisone) are used to reduce inflammation in moderate to severe exacerbations.
  • Oxygen therapy may be needed to maintain adequate saturation.

Memory trick: Asthma Attack: Albuterol First, Breathe Better Fast!

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