NCLEX-PN® ExaminationSafety and Infection ControlEasy

An LPN is preparing to administer a subcutaneous injection to a client. The LPN has drawn up 0.5 mL of medication. Which needle size is most appropriate for this injection?

  1. A20-gauge, 1-inch needle
  2. B18-gauge, 1 1/2-inch needle
  3. C22-gauge, 1/2-inch needle
  4. D25-gauge, 5/8-inch needle
Show answer & explanation

Correct answer: D. 25-gauge, 5/8-inch needle

Subcutaneous injections typically use a small gauge needle (25-30 gauge) and a short length (1/2 to 5/8 inch) to deposit medication into the subcutaneous tissue layer without reaching muscle. A 25-gauge, 5/8-inch needle fits these criteria.

Why the other options are wrong

  • A. A 20-gauge, 1-inch needle is too large in gauge and too long for a subcutaneous injection; it is more suitable for intramuscular injections.
  • B. An 18-gauge, 1 1/2-inch needle is too large in both gauge and length, typically used for drawing up viscous medications or for intramuscular injections in larger muscles.
  • C. A 22-gauge, 1/2-inch needle is a possibility, but 25-gauge is generally preferred for less pain in subcutaneous injections, and 5/8-inch is a common standard length for adults if pinching the skin.

Subcutaneous Injection Needle Selection

The process of choosing the correct needle gauge and length for a subcutaneous injection, aiming to deposit medication into the adipose tissue layer beneath the dermis while minimizing pain and tissue damage.

  • Gauge: 25-30 G (smaller numbers = larger diameter).
  • Length: 1/2 to 5/8 inch (12-16 mm).
  • Injection angle: 45 or 90 degrees, depending on client's body fat.
  • Common sites: abdomen, outer aspect of upper arms, thighs.

Memory trick: Gauge Goes Small, Length is Short for SubQ

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