NCLEX-PN® ExaminationPharmacological TherapiesMedium

A client is prescribed oral ferrous sulfate for iron deficiency anemia. The LPN should instruct the client to take this medication with which of the following to enhance absorption?

  1. AMilk
  2. BCoffee
  3. COrange juice
  4. DAntacids
Show answer & explanation

Correct answer: C. Orange juice

Vitamin C (ascorbic acid) significantly enhances the absorption of non-heme iron, such as that found in ferrous sulfate. Orange juice is rich in Vitamin C, making it an excellent choice to take with iron supplements.

Why the other options are wrong

  • A. Milk and other dairy products contain calcium, which can interfere with iron absorption.
  • B. Coffee, tea, and other caffeinated beverages contain tannins that can inhibit iron absorption.
  • D. Antacids reduce stomach acid, which is necessary for optimal iron absorption, thus decreasing its effectiveness.

Iron Absorption Enhancement

Certain substances, particularly Vitamin C, can significantly increase the bioavailability and absorption of oral iron supplements.

  • Vitamin C enhances iron absorption.
  • Avoid calcium, antacids, coffee, tea.
  • Empty stomach preferred if tolerated.

Memory trick: Iron's Best Friend is Vitamin C; Enemies are Milk and Tea!

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