AANP Family Nurse Practitioner (FNP) Certification ExamAssessmentMedium

A 4-year-old child is brought to the clinic by her mother, who reports a 3-day history of fever (up to 102°F), poor appetite, and irritability. On examination, the nurse practitioner observes multiple small, painful vesicles and ulcers on the buccal mucosa and tongue, along with a maculopapular rash on the palms and soles. The child's immunizations are up-to-date. What is the most appropriate management plan?

  1. ARefer to pediatric infectious disease for IV immunoglobulin
  2. BOrder a rapid strep test and prescribe antibiotics if positive
  3. CPrescribe oral acyclovir for 7 days
  4. DAdvise supportive care with hydration and pain management
Show answer & explanation

Correct answer: D. Advise supportive care with hydration and pain management

The symptoms (fever, oral vesicles/ulcers, rash on palms/soles) are classic for Hand-Foot-and-Mouth Disease (HFMD), which is caused by coxsackievirus. HFMD is a viral illness that is typically self-limiting and requires only supportive care, focusing on hydration and pain relief.

Why the other options are wrong

  • A. IV immunoglobulin is reserved for severe, life-threatening viral infections, not routine HFMD.
  • B. The rash and oral lesions are not consistent with streptococcal pharyngitis, and antibiotics are ineffective against viral infections.
  • C. Acyclovir is an antiviral for herpes simplex, not typically used for coxsackievirus.

Hand-Foot-Mouth Disease (HFMD)

A common viral illness, usually caused by coxsackievirus, characterized by fever, oral lesions (vesicles/ulcers), and a rash on the hands and feet.

  • Caused by coxsackievirus.
  • Classic triad: fever, oral enanthem, exanthem on palms/soles.
  • Self-limiting, managed with supportive care.

Memory trick: Rash with Fever: Think Viral, Treat Supportively

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