AANP Family Nurse Practitioner (FNP) Certification ExamAssessmentEasy

A 5-year-old child presents with a 3-day history of fever, malaise, and a 'slapped-cheek' rash on the face, followed by a lacy, reticular rash on the trunk and extremities. The child is otherwise active and well-appearing. Which of the following is the most likely causative agent?

  1. ARubella virus
  2. BMeasles virus
  3. CVaricella-zoster virus
  4. DParvovirus B19
Show answer & explanation

Correct answer: D. Parvovirus B19

The classic 'slapped-cheek' rash followed by a lacy, reticular rash on the trunk and extremities is pathognomonic for Erythema Infectiosum, also known as Fifth Disease, which is caused by Parvovirus B19.

Why the other options are wrong

  • A. Rubella presents with a maculopapular rash, often starting on the face and spreading quickly, but without the 'slapped-cheek' appearance.
  • B. Measles presents with a maculopapular rash that starts on the face and spreads downwards, often preceded by Koplik spots.
  • C. Varicella-zoster virus causes chickenpox, characterized by vesicular lesions in various stages of healing.

Erythema Infectiosum (Fifth Disease)

A common childhood viral illness caused by Parvovirus B19, characterized by a distinctive facial rash.

  • Also known as 'Fifth Disease'.
  • Classic 'slapped-cheek' rash.
  • Followed by a lacy, reticular rash on body.

Memory trick: Parvo's 'P' is for 'Painted' Cheeks.

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