PTCB Certified Pharmacy Technician (PTCE)MedicationsEasy
A pharmacy technician is preparing a sterile intravenous admixture in a laminar airflow workbench (LAFW). Which of the following actions is critical to maintain the sterility of the compounding environment?
- APlacing all necessary supplies into the LAFW at least 30 minutes before compounding.
- BUsing a new pair of sterile gloves after every admixture preparation.
- CWorking at least six inches inside the LAFW to prevent contamination.
- DWiping down the workbench surfaces with 70% isopropyl alcohol every 8 hours.
Show answer & explanationAnswer & explanation
Correct answer: C. Working at least six inches inside the LAFW to prevent contamination.
Working at least six inches inside the LAFW is crucial because it ensures that compounding activities occur within the 'first air' zone, which is the area directly exposed to the HEPA-filtered air, minimizing the risk of contamination from the outside environment.
Why the other options are wrong
- A. Placing supplies in advance is good practice for temperature equilibration, but not directly critical for maintaining sterility during the active compounding process.
- B. While good practice, changing gloves after every admixture might be excessive; gloves should be changed if contaminated or integrity is compromised, not necessarily after every single preparation.
- D. Wiping down surfaces is important, but typically done before compounding and every 30 minutes during continuous compounding, not just every 8 hours for critical sterility.
LAFW 'First Air' Zone
The critical area inside a Laminar Airflow Workbench (LAFW) where uncontaminated, HEPA-filtered air flows directly over the compounding activities, ensuring sterility.
- Compounding activities must occur within this zone.
- Typically at least six inches inside the LAFW's front edge.
- Prevents turbulent airflow and introduction of contaminants.
Memory trick: Aseptic means no germs, keep air flowing clean.