PTCB Certified Pharmacy Technician (PTCE)Patient Safety and Quality AssuranceEasy

A pharmacy technician is preparing to compound a hazardous sterile preparation. Which of the following primary engineering controls (PECs) is MOST appropriate for this task?

  1. ABiological Safety Cabinet (BSC) Class II, Type B2
  2. BCompounding Aseptic Containment Isolator (CACI)
  3. CCompounding Aseptic Isolator (CAI)
  4. DLaminar Airflow Workbench (LAFW)
Show answer & explanation

Correct answer: B. Compounding Aseptic Containment Isolator (CACI)

For hazardous sterile preparations, a Compounding Aseptic Containment Isolator (CACI) is required. It provides both product protection and operator protection by maintaining negative pressure and filtering exhaust air.

Why the other options are wrong

  • A. While BSCs provide operator protection, a CACI is specifically designed for sterile compounding of hazardous drugs, offering both containment and aseptic conditions.
  • C. CAIs are for non-hazardous sterile preparations and do not provide operator protection from hazardous drugs.
  • D. LAFWs are for non-hazardous sterile preparations and do not provide operator protection from hazardous drugs.

Compounding Aseptic Containment Isolator (CACI)

A CACI is a specific type of isolator used for compounding hazardous sterile preparations, providing both an aseptic environment for the product and containment for the operator.

  • Used for hazardous sterile compounding.
  • Provides negative pressure for operator safety.
  • Filters exhaust air to prevent environmental contamination.

Memory trick: Hazardous drugs need a CACI, keeping workers safe and products neat.

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