MCAT® ExamBiological and Biochemical Foundations of Living SystemsEasy

A research team is investigating a novel protein that acts as a receptor for a specific hormone. They discover that when the hormone binds to the receptor, it induces a conformational change that allows a G-protein to bind and become activated. This activated G-protein then initiates a cascade of intracellular events. Which of the following best describes this process?

  1. ADirect gene activation
  2. BEnzymatic catalysis
  3. CSignal transduction
  4. DPassive diffusion
Show answer & explanation

Correct answer: C. Signal transduction

This scenario describes a classic example of signal transduction, where an extracellular signal (hormone binding) is converted into an intracellular response through a series of molecular events.

Why the other options are wrong

  • A. Direct gene activation typically involves steroid hormones that directly enter the cell and bind to intracellular receptors.
  • B. Enzymatic catalysis refers to the acceleration of biochemical reactions by enzymes, which is a component but not the overarching process described.
  • D. Passive diffusion is the movement of substances across a membrane without energy expenditure, not a complex cellular signaling pathway.

Signal Transduction

The process by which a cell converts an extracellular signal into an intracellular response, often involving a series of molecular events.

  • Involves receptors binding to ligands.
  • Leads to a cascade of intracellular events.
  • Allows cells to respond to their environment.

Memory trick: Signals Transmit Responses

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