MCAT® ExamBiological and Biochemical Foundations of Living SystemsHard

A scientist is studying a newly discovered single-celled organism found in an extreme environment near a deep-sea hydrothermal vent. Microscopic analysis reveals that the organism lacks a membrane-bound nucleus, mitochondria, and endoplasmic reticulum. Its cell wall does not contain peptidoglycan. This organism is most likely a member of which domain?

  1. AProtista
  2. BArchaea
  3. CBacteria
  4. DEukarya
Show answer & explanation

Correct answer: B. Archaea

The absence of a membrane-bound nucleus and organelles indicates a prokaryotic organism (Bacteria or Archaea). The absence of peptidoglycan in the cell wall, combined with its extremophilic habitat (deep-sea hydrothermal vent), strongly points to Archaea, as Bacteria typically have peptidoglycan and Eukarya are characterized by membrane-bound organelles and a nucleus.

Why the other options are wrong

  • A. Protista are eukaryotic organisms and would possess a nucleus and mitochondria.
  • C. Bacteria lack a membrane-bound nucleus and mitochondria, but their cell walls typically contain peptidoglycan.
  • D. Eukarya would have a membrane-bound nucleus and mitochondria.

Characteristics of Archaea

A domain of single-celled organisms that are prokaryotes (lack a nucleus and membrane-bound organelles), have cell walls without peptidoglycan, and often thrive in extreme environments.

  • Prokaryotic (no nucleus, no membrane-bound organelles).
  • Cell walls lack peptidoglycan (unlike Bacteria).
  • Distinct rRNA sequences from Bacteria and Eukarya.
  • Many are extremophiles (thermophiles, halophiles, methanogens).
  • Unique membrane lipids (ether linkages, branched hydrocarbons).

Memory trick: Archaea's Arch-nemesis: Peptidoglycan! And they love Extreme sports!

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