MCAT® ExamChemical and Physical Foundations of Biological SystemsMedium

A laboratory technician is preparing a solution for an experiment. They need to dilute a 2.0 M stock solution of hydrochloric acid (HCl) to obtain 500 mL of a 0.25 M HCl solution. What volume of the stock solution is required for this dilution?

  1. A50.0 mL
  2. B62.5 mL
  3. C125 mL
  4. D25.0 mL
Show answer & explanation

Correct answer: B. 62.5 mL

This is a dilution problem that can be solved using the formula M₁V₁ = M₂V₂. Given: M₁ = 2.0 M (stock concentration), V₁ = ? (volume of stock), M₂ = 0.25 M (desired concentration), V₂ = 500 mL (desired volume). Rearranging the formula to solve for V₁: V₁ = (M₂V₂) / M₁. V₁ = (0.25 M × 500 mL) / 2.0 M V₁ = 125 M⋅mL / 2.0 M V₁ = 62.5 mL.

Why the other options are wrong

  • A. Incorrect calculation: (0.25 * 500) / 2.5
  • C. Incorrect calculation: (0.50 * 500) / 2.0
  • D. Incorrect calculation: (0.25 * 500) / 5.0

Dilution Equation

The dilution equation, M₁V₁ = M₂V₂, is used to calculate the concentration or volume of a solution before or after dilution, assuming the amount of solute remains constant.

  • M₁ = initial molarity (concentration of stock solution).
  • V₁ = initial volume (volume of stock solution needed).
  • M₂ = final molarity (desired concentration of diluted solution).
  • V₂ = final volume (desired total volume of diluted solution).
  • Units for volume must be consistent (e.g., both mL or both L).

Memory trick: Mighty Vials Make Very easy dilutions!

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