MCAT® ExamChemical and Physical Foundations of Biological SystemsMedium

A patient is undergoing a medical scan that utilizes a radioactive isotope with a half-life of 6 hours. If the initial activity of the isotope is 800 MBq, what will be the approximate activity after 18 hours?

  1. A100 MBq
  2. B400 MBq
  3. C200 MBq
  4. D50 MBq
Show answer & explanation

Correct answer: A. 100 MBq

The half-life is 6 hours. The total time elapsed is 18 hours. Number of half-lives = Total time / Half-life = 18 hours / 6 hours = 3 half-lives. After 1 half-life: 800 MBq / 2 = 400 MBq. After 2 half-lives: 400 MBq / 2 = 200 MBq. After 3 half-lives: 200 MBq / 2 = 100 MBq.

Why the other options are wrong

  • B. This would be the activity after 1 half-life.
  • C. This would be the activity after 2 half-lives.
  • D. This would be the activity after 4 half-lives.

Radioactive Half-Life

The time it takes for half of the radioactive nuclei in a sample to decay, or for the activity of a radioactive sample to decrease by half.

  • Half-life is a constant for a given isotope and is independent of initial concentration, temperature, or pressure.
  • After 'n' half-lives, the remaining amount (or activity) is (1/2)ⁿ of the initial amount.
  • Radioactive decay follows first-order kinetics.
  • It's used in medicine for diagnostics (e.g., PET scans) and therapy.

Memory trick: Divide by two, count the halves, and you're through!

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