NCLEX-RNPharmacological and Parenteral TherapiesMedium

A client is scheduled to receive a unit of platelets. The client's temperature is 100.8°F (38.2°C) orally. The provider has been notified of the fever and states to proceed with the transfusion. Which action should the nurse take before starting the platelet transfusion?

  1. AEnsure a new transfusion consent form is signed by the client.
  2. BInitiate a new peripheral IV line in the opposite arm.
  3. CCheck the client's most recent complete blood count (CBC).
  4. DAdminister an ordered antipyretic and reassess temperature in 30 minutes.
Show answer & explanation

Correct answer: D. Administer an ordered antipyretic and reassess temperature in 30 minutes.

Platelet transfusions are often given to prevent or treat bleeding in thrombocytopenic clients. A pre-existing fever can mask a febrile non-hemolytic transfusion reaction (FNHTR) or worsen other transfusion reactions. Administering an ordered antipyretic can help reduce the fever, making it easier to identify new febrile reactions and improving client comfort. Since the provider has cleared the transfusion, addressing the fever is the most appropriate next step.

Why the other options are wrong

  • A. Transfusion consent is typically obtained once for the admission or a course of treatment, not for each individual unit, unless policy dictates or client status changes significantly.
  • B. While a new IV line might be needed if the current one is compromised, there is no information to suggest this. It's not the priority action related to the fever.
  • C. A recent CBC is important for determining the need for platelets, but it's usually obtained before the order is placed, and checking it again just before transfusion doesn't address the immediate concern of the fever.

Pre-Transfusion Fever Management

A pre-existing fever in a client scheduled for a blood product transfusion can obscure the signs of a febrile non-hemolytic transfusion reaction (FNHTR). If the provider clears the transfusion despite the fever, administering an ordered antipyretic can help differentiate between the baseline fever and a new transfusion-related febrile event.

  • Fever can mask transfusion reactions.
  • Antipyretics reduce baseline fever.
  • Provider approval is key.
  • FNHTR is a common transfusion reaction.

Memory trick: Fever before blood? Medicate, then proceed if okay'd!

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