NCLEX-RNReduction of Risk PotentialHard

A client sustained a closed fracture of the femur 20 hours ago and is awaiting surgical repair. The nurse notes new-onset confusion, a respiratory rate of 32/min, oxygen saturation of 89% on room air, and a petechial rash across the chest and axillae. Which complication should the nurse suspect?

  1. ADeep vein thrombosis
  2. BCompartment syndrome
  3. CHypovolemic shock
  4. DFat embolism syndrome
Show answer & explanation

Correct answer: D. Fat embolism syndrome

The classic triad of fat embolism syndrome is hypoxemia, neurologic changes (confusion), and a petechial rash, typically occurring 12–72 hours after a long-bone fracture. Fat globules released from bone marrow travel to the pulmonary and cerebral circulation, causing these findings.

Why the other options are wrong

  • A. DVT presents with unilateral leg swelling, warmth, and pain, not petechiae or confusion.
  • B. Compartment syndrome causes localized limb pain and pallor, not systemic petechiae or confusion.
  • C. Hypovolemic shock presents with hypotension and tachycardia, not a petechial rash.

Fat Embolism Syndrome

A complication of long-bone or pelvic fractures where fat globules enter the bloodstream, causing respiratory distress, neurologic changes, and petechiae, usually within 12–72 hours of injury.

  • Classic triad: hypoxemia, altered mental status, petechial rash
  • Occurs 12–72 hours after long-bone fracture
  • Petechiae typically on chest, axillae, and conjunctivae
  • Treatment is supportive: oxygen, early fracture stabilization, monitoring

Memory trick: 'Fat FLEES the bone: Fever/confusion, Lung hypoxia, Erythema/petechiae, 12-72hrs, Emergency Stabilize.'

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